There is no dedicated non-proliferation regime imposed by the United Nations.
There is no dedicated non-proliferation regime imposed by EU. However, proliferation concerns are addressed in other programs like Iran and North Korea regimes.
There are two sanction programs with respect to non-proliferation administered by the U.S. Treasury. One imposes Financial Sanctions and the other imposes trade and financial sanctions.
The Trade Sanctions are imposed pursuant to E.O. 12938 and are codified under Weapons of Mass Destruction Trade Control Regulations, 31 C.F.R PART 539. It prohibits the importation into the United States of any goods, technology, or services produced or provided by a designated foreign person, other than information or informational materials. Also, there are limited financial sanctions in this program which prohibits any transactions related to such imports.
The Financial Sanctions of the United States non-proliferation program are imposed pursuant to E.O. 13382 and are codified under part 544 of title 31 of C.F.R. These authorities imposes asset freezing obligations on U.S. persons. Those listed under this sanction program are listed on the OFAC SDN list carrying the tag of [NPWMD]. There are more than a thousand entries with [NPWMD] on the SDN list.
There is no Foreign Financial Institutions secondary sanctions type in this program; however, any person could be designated if it provides support to one which is listed under this program.
Highly Enriched Uranium (HEU) Agreement Assets Control Regulations (31 C.F.R. 540) used to be another program under the non-proliferation sanctions scheme of the United stated. This program does not exist anymore as the U.S. President, through E.O. 13695, terminated the National Emergency which had created this program.
The Department of State has a dedicated page for non-proliferation sanctions. (Click here.)